Sotyktu: Side Effects, Cost, Uses, Dosage |


What is Sotyktu?

 Your physician might advise using Sotyktu as a form of therapy if you have plaque psoriasis. It's a prescription drug that some people use to treat mild or severe plaque psoriasis. See the part below titled "Is Sotyktu used for plaque psoriasis?" for more information.

A suppressor of the immune system is Sotyktu. (a drug that weakens your immune system). It's essential to remember that Sotyktu shouldn't be taken with potent immunosuppressants. For more information, see the part below titled "Is Sotyktu used for plaque psoriasis?".

Sotyktu basics

Deucravacitinib is the main component in Sotyktu. (An active ingredient is what makes a drug work.) You take a pill form of it to take it.

Tyrosine kinase 2 antagonists, which include Sotyktu, are a class of medications. Drug Sotyktu is a biopharmaceutical. Biological medicine is created using biological organisms. Sotyktu is only marketed under its brand name. For Sotyktu, there isn't a copycat. (Biosimilars resemble common medications. However, biosimilars are created for biologic drugs, as opposed to generics, which are created for nonbiologic medications.)

Learn more about Sotyktu, including its purposes, price, and adverse effects, by reading on.

What are Sotyktu’s side effects?

Sotyktu, like most medications, could have minor or major adverse effects. Some of the more frequent adverse effects that Sotyktu may have are listed below. These inventories do not cover every potential adverse impact.

Remember that a drug's adverse effects can vary depending on:

  • your age
  • other medications you take
  • other health conditions you have

You can learn more about Sotyktu's possible adverse effects from your doctor or pharmacist. They may offer solutions to lessen adverse impacts.

Mild side effects

The minor adverse effects that Sotyktu may have are listed below. Read the prescription instructions for Sotyktu or consult your doctor or pharmacist to learn more about additional mild side effects.

Sotyktu has been associated with a few mild adverse effects, including:

  • mild allergic reaction†
  • reactivation of herpes (if you’ve contracted this virus in the past)
  • high levels of liver enzymes*
  • high level of triglycerides (a kind of fat in the blood)
  • folliculitis (inflammation of the hair follicles)
  • acne
  • mouth sores
  • mild upper respiratory infection, such as a sinus infection

Many medications' mild adverse effects may disappear in a few days to a few weeks. However, if they start to trouble you, consult your doctor or pharmacy.

* Elevated liver enzyme values may indicate injury or issues with the liver. But Sotyktu's research didn't find any evidence of liver harm.

† Check out the part below titled "Allergic reaction" to learn more about this adverse effect.

Serious side effects

Although they are rare, serious adverse effects from Sotyktu can happen. Call your doctor right away if Sotyktu causes any severe adverse effects. However, you should dial 911 or your local emergency number if you believe you are experiencing a medical emergency.

The following are serious adverse effects of Sotyktu that have been reported:

  • a kind of muscle damage called rhabdomyolysis
  • cancer, including lymphoma
  • increased risk of serious infection, such as pneumonia and COVID-19
  • severe allergic reaction*

What does Sotyktu cost?

Prescription drug costs can differ based on several variables. These variables include the coverage provided by your insurance and the store you use.

Speak to your physician or pharmacist if you have any concerns about how to pay for your medication. There may also be a programme named Sotyktu 360 Support.

To learn more about reducing the cost of prescribed medications, you can also read this piece.

Is Sotyktu used for plaque psoriasis?

Adults with mild to severe plaque psoriasis are treated with Sotyktu. Adults who are being treated with systemic therapy or phototherapy (light therapy) are specifically given the medication. (treatment that affects the whole body).

Targeting an enzyme (protein) in the body that is believed to cause inflammation is how Sotyktu addresses plaque psoriasis. (swelling or damage). Plaque psoriasis signs can be treated by decreasing irritation.

A suppressor of the immune system is Sotyktu. (a drug that weakens your immune system). It's significant to remember that Sotyktu shouldn't be taken with other immunosuppressants.

When combined with other immunosuppressants, Sotyktu may cause an excessively weakened immune system that increases the chance of illness. Serious diseases like COVID-19 or TB may fall under this category.

About plaque psoriasis

The most prevalent type of psoriasis is plaque psoriasis. A persistent (long-lasting) autoimmune disease, psoriasis. When you have an autoimmune disease, your immune system's mistakenly targeting other cells in your body leads to symptoms.

When your immune system attacks healthy skin cells, it can lead to plaque psoriasis. As a result, new skin cells replace damaged or dead skin cells more rapidly than normal. Plaques—raised, scaly, dense areas of skin—are the result of this. Plaques from psoriasis can develop anywhere on your body, but they usually do so on your:

  • elbows
  • back
  • scalp
  • face
  • hands
  • knees

Psoriasis lesions typically resemble:

  • pink or red with white scales on lighter skin
  • purple or brown with grey scales on darker skin


What does SOTYKTU do?

Adults with moderate-to-severe plaque psoriasis who are qualified to receive systemic treatment (injections or tablets) or phototherapy can take the drug Sotyktu (deucravacitinib). (treatment using ultraviolet or UV light).

What class of drug is SOTYKTU?

Tyrosine kinase 2 (TYK2) inhibitors, of which Sotyktu is one member, are a family of medications.

When is the best time to take SOTYKTU?

It can be challenging to manage mild to serious plaque psoriasis. You consume a once-daily tablet for SOTYKTU. You can use SOTYKTU whenever and wherever it works best for your everyday schedule.

What are the ingredients in SOTYKTU?

The active substance is deucravacitinib. Anhydrous lactose, silicon dioxide, microcrystalline cellulose, magnesium stearate, hypromellose acetate succinate, and croscarmellose sodium are inert substances.

What is Sotyktu’s dosage?

Your specialist will advise you on the appropriate Sotyktu dose. The doses listed below are typical ones, but you should always follow your doctor's instructions.

Shape and power

You must take a pill called Sotyktu. There is only one 6-milligramme level available. (mg).

Suggested Dose

The suggested Sotyktu dosage is 6 mg given once daily for the treatment of plaque psoriasis.

Concerns regarding Sotyktu's dosage

Here are some frequently asked queries about Sotyktu's dosage.

What if I miss a dose of Sotyktu?

Try to take the missed Sotyktu dosage as soon as you recall it if you do. Take your next dosage as directed if you miss a day, though. Sotyktu should not be taken more than once daily.

Will I need to take Sotyktu long-term?

Yes. You'll probably continue taking Sotyktu for a long time if both you and your doctor decide it's safe and effective for you.

How long does Sotyktu take to work?

With your first dosage of Sotyktu, it starts to function. However, it might take between 16 and 24 weeks for the medication to have its full impact and relieve your plaque psoriasis symptoms.

What things need to be thought about before consuming Sotyktu?

Interactions A medication's effectiveness may be impacted by the use of specific meals, immunizations, and other substances. Interactions are the term for these outcomes.

Tell your doctor about all of your current medicines, both prescribed and non-prescription, before taking Sotyktu. Include a description of any supplements, plants, or minerals you take. You can learn more about any possible conflicts between these substances and Sotyktu from your doctor or chemist.

See the "Warnings" part below for details on drug-condition complications.

Medication interactions or supplement interactions

There aren't any drugs or nutritional products that have been known to combine with Sotyktu as of yet. However, this does not preclude future research on medication reactions with Sotyktu. For instance, novel drugs that combine with Sotyktu might be authorised.

You should still let your doctor and pharmacy know about any medicines you take in addition to Sotyktu because of this. By doing this, they can monitor your medication for any novel interactions.

A suppressor of the immune system is Sotyktu. (a drug that weakens your immune system). The use of Sotyktu with other potent immunosuppressants like cyclosporine (Gengraf, Neoral, Sandimmune) and mycophenolate mofetil is not advised. (CellCept). The interaction of Sotyktu with these other medications has not been investigated.

Additional encounters

Receiving a live immunisation while taking Sotyktu is not advised. (Live vaccines contain a weakened form of the virus or bacterium they protect against.)

If you receive a live immunisation while taking Sotyktu, you run the risk of getting ill from the virus in the vaccine.

Live immunisations include, for instance:

  • yellow fever vaccine
  • nasal (nose) spray flu vaccine (FluMist)
  • measles, mumps, rubella (MMRTrusted Source) vaccine
  • chickenpox vaccine

Ask your doctor if you need any immunisations before taking Sotyktu. Before beginning therapy with Sotyktu, your doctor might advise that you get them.


In some cases, sotyktu can be detrimental to those who already have certain medical problems. An adverse drug-condition combination is what this is. If Sotyktu is a viable treatment choice for you, it may also depend on other factors.

Before taking Sotyktu, discuss your medical background with your doctor. The following factors are among those to take into account.

Active* infection

Before taking Sotyktu, inform your doctor if you have an illness (or signs of an infection, such as a rash or fever). Your immune system is weakened by this medication, which makes it more difficult to cure illnesses. Before you begin to take Sotyktu, your doctor will probably want to address any illness.

Hepatitis B or hepatitis C

Inform your doctor if you have ever had hepatitis B or C before beginning Sotyktu therapy. Your doctor won't recommend Sotyktu if you have an ongoing hepatitis B or C virus; instead, they'll look at other treatment options.

An inactive* virus could also become active when exposed to sotyktu. (cause symptoms again). Your doctor will decide whether Sotyktu is suitable for you to take if you've previously had hepatitis B or C.


Before taking Sotyktu, let your doctor know if you've ever had tuberculosis (TB) or have been in direct touch with someone who has. Your doctor will examine you to see if you have TB right now. As long as their TB has been treated and is no longer infectious, they can take Sotyktu. Your doctor will keep an eye out for infection signs, such as TB infection, while you are receiving Sotyktu therapy.

Allergic reaction

Your doctor is unlikely to recommend Sotyktu if you've previously experienced an adverse response to any of the medication's components. Find out from them which other medicines would be best for you.

* A viral infection is said to be active when it is presently producing symptoms. A dormant viral infection does not exhibit signs.

Sotyktu and alcohol

Alcohol and Sotyktu don't seem to mix at all.

Alcohol may impair your immune system, but sotyktu also does. A compromised immune system increases your vulnerability to illness. Therefore, consuming booze while taking Sotyktu increases your chance of infection.

After consuming booze, some people's psoriasis symptoms get worse.

Consult your doctor if you imbibe and have any concerns about doing so while taking Sotyktu.

Nursing and being pregnant

It is unknown if taking Sotyktu while expecting is healthy. Discuss the suitability of Sotyktu with your doctor if you are expecting or intend to become pregnant.

Also unclear is the safety of using Sotyktu while nursing a baby. Before taking Sotyktu, discuss nursing or plans to nurse with your doctor.

How is Sotyktu taken?

How to take Sotyktu will be explained to you by your doctor. They'll also go over how much and how frequently to take it. Make careful to adhere to your doctor's recommendations.

Consuming Sotyktu

You must take a pill called Sotyktu.

Accessible drug packaging and markings

Inform your doctor or pharmacist if it is difficult for you to understand the notice on your medication. Some shops might offer drug labels that:

  • have large print
  • contain a code you can scan with a smartphone to change the text into audio
  • use braille

If your present pharmacy doesn't provide these choices, your doctor or pharmacist might be able to suggest one that does.

Additionally, tell your chemist if you're having difficulty opening the packages of your prescription drugs. They might be able to place Sotyktu in a package that is simple to access. Additionally, your pharmacist might suggest equipment to make it easier to access the drug's packaging.

Concerns about consuming Sotyktu

The queries and answers about using Sotyktu are listed below.

Can you chew, pulverize, or divide Sotyktu?

 The pills of Sotyktu should not be chewed, crushed, or divided. Check out these suggestions or consult your doctor or pharmacist if you're having difficulty taking pills.

Should I eat before taking Sotyktu? 

Sotyktu can be taken with or without meals.

What time of day is ideal for taking Sotyktu?

 No, the ideal time of day to consume Sotyktu is not specific. As directed by your doctor, take your medication once daily.

In the event of an accident, what should be done?

Take Sotyktu only as directed by your doctor. This may have negative adverse effects on some medicines.

How to react if you consume too much Sotyktu

If you suspect you've taken too much Sotyktu, call your doctor right away. You can contact America's Poison Centers online or by dialling 800-222-1222. 

But if your symptoms are serious, dial 911 or your local emergency number right away. Alternatively, visit the closest emergency centre.

What to question your doctor

Some people with moderate to severe plaque psoriasis are given sotyktu.

Speak to your doctor or chemist if you have any concerns about taking Sotyktu. You might want to pose the following questions:

  • How effective is Sotyktu in treating mild to severe plaque psoriasis compared to other medications?
  • Is there a reduced dose of Sotyktu I can attempt if I experience side effects?
  • Do I need to take extra measures while taking Sotyktu, such as donning a mask in public places to help avoid infection?

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Disclaimer: Juthow has taken every precaution to ensure that all material is truly accurate, thorough, and current. However, the knowledge and experience of a qualified healthcare practitioner should always be sought after instead of using the information in this piece. Before taking any medicine, you should always speak to your doctor or another qualified healthcare provider. The material provided here about medications is open to change and is not meant to include all uses, notes, warnings, instructions, drug interactions, allergic responses, or negative effects. The lack of caution or other information for a particular medication does not imply that the medication or medication combo is suitable for all people or all possible purposes.